Antibody
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Simulation of which
of the following will lead to appearance of first antibody to appear following
stimulation by an antigen?
a. IgM
b. IgA
c. IgE
d. IgG
Antigen binding sites
of an immunoglobulin are located in___________.
a. light
chain alone
b. heavy
chain alone
c. Fc region
of the antibody
d. Fab regions of the antibody
Anti-Rh antibodies
are___________.
a. IgG type
b. IgA type
c. IgE type
d. IgD type
Which is not a
function of IgA?
a. Protect
mucosal surfaces
b. Fix complement
c. Protect
eyes
d.
Agglutinate antigen
J chain is present in___________.
a. IgA
b. IgM
c. Both (a) and (b)
d. IgE
Heat-labile class of
immunoglobulins include___________.
a. IgA
b. IgE
c. IgG
d. IgM
Which of the
following mediates Type I hypersensitivity reaction?
a. IgE
b. IgG
c. IgM
d. IgD
Which of the
following theory of antibody production is most widely accepted?
a. Side chain
theory
b. Clonal selection theory
c. Direct
template theory
d. Indirect
template theory
Which is the most
efficient complement fixing class of antibody?
a. IgE
b. IgA
c. IgM
d. IgG
Which of the
following is the phylogenetically oldest immunoglobulin?
a. IgE
b. IgM
c. IgG
d. All are
similar
The secretary
component of sIgA is___________.
a. made by
plasma cells that secrete dimeric IgA
b. added to
dimeric IgA by the M cell
c. formed by cleavage of an epithelial
cell receptor used to transport the dimeric IgA across the epithelial cell
d. made by T
cells
The class of
immunoglobulins which can cross the placenta is___________.
a. IgM
b. IgG
c. IgA
d. IgD
Self reactive
antibodies are not found in significant concentration in normal serum because___________.
a. it is
impossible to generate a self-reactive antibody
b. self
reactive B cells are killed by CD8 T cells
c. B cells that are stimulated via
their surface bound antibody in the absence of T cell help to commit suicide
d. self
reactive B cells switch to IgA which is all secreted and not present in serum
The class of
immunoglobulin, most abundant in body is___________.
a. IgD
b. IgE
c. IgG
d. IgM
Which is not a
function of IgG?
a. Major
antibody in serum
b. First antibody type produced
against an antigen during the primary antibody response
c. Activates
or fixes complement
d. Involved
in opsonization
Which of the
following (s) is/are function (s) of Fc fragment of IgG?
a. It
determines catabolic rate
b. It binds
complement
c. It is
related to passage of IgG across the placental barrier
d. All of these